Institut für Organische Chemie
Postadresse: Währingerstraße 38, 1090 Wien
Österreich
E-Mail: katharina.pallitsch@univie.ac.at
Telefon: +43-1-4277-52105 bzw. 52123
Veröffentlichungen
Decrypting the function of recurrent ancillary enzymes in bacterial phosphonate catabolism
Ruffolo, F., Zangelmi, E., Dinhof, T., Malatesta, M., Gerdol, M., Chin, J. P., Secchi, A., Rivetti, C., Pallitsch, K. & Peracchi, A., Juni 2024, in: FEBS Open Bio. 14, Supplement: 2, S. 153-154 P-11-003.Development and In Vivo Evaluation of Small-Molecule Ligands for Positron Emission Tomography of Immune Checkpoint Modulation Targeting Programmed Cell Death 1 Ligand 1
Bamminger, K., Pichler, V., Vraka, C., Limberger, T., Moneva, B., Pallitsch, K., Lieder, B., Zacher, A. S., Ponti, S., Benčurová, K., Yang, J., Högler, S., Kodajova, P., Kenner, L., Hacker, M. & Wadsak, W., 14 März 2024, in: Journal of Medicinal Chemistry. 67, 5, S. 4036-4062 27 S.Asymmetric Transfer Hydrogenation as a Key Step in the Synthesis of the Phosphonic Acid Analogs of Aminocarboxylic Acids
Dinhof, T., Kalina, T., Stanković, T., Braunsteiner, K., Rohrbach, P., Turhan, E., Gradwohl, A., Königshofer, A., Horak, J. & Pallitsch, K., 22 Dez. 2023, in: Chemistry - A European Journal. 29, 72, e202302171.Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism
Zangelmi, E., Ruffolo, F., Dinhof, T., Gerdol, M., Malatesta, M., Chin, J. P., Rivetti, C., Secchi, A., Pallitsch, K. & Peracchi, A., 17 Nov. 2023, in: Iscience. 26, 11, 108108.Synthesis of 4-Deoxy-4-Fluoro-D-Sedoheptulose: A Promising New Sugar to Apply the Principle of Metabolic Trapping
Scheibelberger, L., Stankovic, T., Pühringer, M., Kählig, H., Balber, T., Patronas, E. M., Rampler, E., Mitterhauser, M., Haschemi, A. & Pallitsch, K., 8 Nov. 2023, in: Chemistry - A European Journal. 29, 62, e202302277.The Microbial Degradation of Natural and Anthropogenic Phosphonates
Ruffolo, F., Dinhof, T., Murray, L., Zangelmi, E., Chin, J. P., Pallitsch, K. & Peracchi, A., Okt. 2023, in: Molecules. 28, 19, 6863.Fluorinated Analogues to the Pentuloses of the Pentose Phosphate Pathway
Scheibelberger, L., Stankovic, T., Liepert, K., Kienzle, A., Patronas, E. M., Balber, T., Mitterhauser, M., Haschemi, A. & Pallitsch, K., 14 Aug. 2023, in: European Journal of Organic Chemistry. 26, 31, e202300339.On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach
Bamminger, K., Pichler, V., Vraka, C., Nehring, T., Pallitsch, K., Lieder, B., Hacker, M. & Wadsak, W., Juli 2023, in: Pharmaceuticals. 16, 7, 1051.The functional importance of bacterial oxidative phosphonate pathways
Pallitsch, K. & Zechel, D. L., Apr. 2023, in: Biochemical Society Transactions. 51, 2, S. 487-499 13 S.Biosynthesis of the Fungal Organophosphonate Fosfonochlorin Involves an Iron(II) and 2-(Oxo)glutarate Dependent Oxacyclase
Gama, S. R., Stankovic, T., Hupp, K., Al Hejami, A., McClean, M., Evans, A., Beauchemin, D., Hammerschmidt, F., Pallitsch, K. & Zechel, D. L., 19 Jan. 2022, in: ChemBioChem: a european journal of chemical biology. 23, 2, 8 S., e202100352.As Similar As Possible, As Different As Necessary - On-Site Laboratory Teaching during the COVID-19 Pandemic
Mosiagin, I., Pallitsch, K., Klose, S. I., Preinfalk, A. & Maulide, N., 12 Okt. 2021, in: Journal of Chemical Education. 98, 10, S. 3143-3152 10 S.Towards understanding the magnetism of Os(iv) complexes: an ab initio insight
Ungur, L., Pallitsch, K., AlOthman, Z. A., Al-Kahtani, A. A. S., Arion, V. B. & Chibotaru, L. F., Aug. 2021, in: Dalton Transactions. 50, 36, S. 12537-12546 10 S.Discovery of melanin-concentrating hormone receptor 1 in brown adipose tissue
Philippe, C., Klebermass, E-M., Balber, T., Kulterer, O. C., Zeilinger, M., Egger, G., Dumanic, M., Herz, C. T., Kiefer, F. W., Scheuba, C., Scherer, T., Fuernsinn, C., Vraka, C., Pallitsch, K., Spreitzer, H., Wadsak, W., Viernstein, H., Hacker, M. & Mitterhauser, M., Juni 2021, in: Annals of the New York Academy of Sciences. 1494, 1, S. 70-86 17 S.Overall Retention of Methyl Stereochemistry during B-12-Dependent Radical SAM Methyl Transfer in Fosfomycin Biosynthesis
McLaughlin, M., Pallitsch, K., Wallner, G., van der Donk, W. A. & Hammerschmidt, F., 25 Mai 2021, in: Biochemistry. 60, 20, S. 1587-1596 10 S.Discovery of a New, Recurrent Enzyme in Bacterial Phosphonate Degradation: (R)-1-Hydroxy-2-aminoethylphosphonate Ammonia-lyase
Zangelmi, E., Stankovic, T., Malatesta, M., Acquotti, D., Pallitsch, K. & Peracchi, A., 20 Apr. 2021, in: Biochemistry. 60, 15, S. 1214-1225 12 S.C-H Bond Cleavage Is Rate-Limiting for Oxidative C-P Bond Cleavage by the Mixed Valence Diiron-Dependent Oxygenase PhnZ
Gama, S. R., Lo, B. S. Y., Seguin, J., Pallitsch, K., Hammerschmidt, F. & Zechel, D. L., 31 Dez. 2019, in: Biochemistry. 58, 52, S. 5271-5280 10 S.(R)-[F-18]NEBIFQUINIDE: A promising new PET tracer for TSPO imaging
Berroteran-Infante, N., Kalina, T., Fetty, L., Janisch, V., Velasco, R., Vraka, C., Hacker, M., Haug, A. R., Pallitsch, K., Wadsak, W. & Mitterhauser, M., 15 Aug. 2019, in: European Journal of Medicinal Chemistry. 176, S. 410-418 9 S.In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes
Balber, T., Bencurova, K., Kiefer, F. W., Kulterer, O. C., Klebermass, E-M., Egger, G., Tran, L., Wagner, K-H., Viernstein, H., Pallitsch, K., Spreitzer, H., Hacker, M., Wadsak, W., Mitterhauser, M. & Philippe, C., 11 Juni 2019, in: Frontiers in Endocrinology. 10, 324.Facilitated troubleshooting in (+)-[C-11]PHNO synthesis by investigation of reagents, byproducts, and intermediates
Pfaff, S., Philippe, C., Nics, L., Berroteran-Infante, N., Pallitsch, K., Rami-Mark, C., Weidenauer, A., Sauerzopf, U., Willeit, M., Mitterhauser, M., Hacker, M., Wadsak, W. & Pichler, V., Mai 2019, in: Journal of Labelled Compounds and Radiopharmaceuticals. 62, S. 255-257 3 S.SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [F-18]FE@SNAP and [C-11]SNAP-7941
Philippe, C., Zeilinger, M., Dumanic, M., Pichler, F., Fetty, L., Vraka, C., Balber, T., Wadsak, W., Pallitsch, K., Spreitzer, H., Lanzenberger, R., Hacker, M. & Mitterhauser, M., 15 Apr. 2019, in: Molecular Imaging and Biology. 21, 2, S. 257-268 12 S.An Oxidative Pathway for Microbial Utilization of Methylphosphonic Acid as a Phosphate Source
Gama, S. R., Vogt, M., Kalina, T., Hupp, K., Hammerschmidt, F., Pallitsch, K. & Zechel, D. L., Apr. 2019, in: ACS Chemical Biology. 14, 4, S. 735-741 7 S.Synthetic Phosphonic Acids as Potent Tools to Study Phosphonate Enzymology
Pallitsch, K., Kalina, T. & Stanković, T., Apr. 2019, in: Synlett. 30, 7, S. 770-776 7 S.Synthesis and in vitro evaluation of new translocator protein ligands designed for positron emission tomography
Kalina, T., Berroterán-Infante, N., Schmitl, S., Vraka, C., Hacker, M., Mitterhauser, M., Pallitsch, K. & Wadsak, W., 1 März 2019, in: Future Medicinal Chemistry. 11, 6, S. 539-550 12 S.Optimization of the Automated Synthesis of [ 11C ]mHED—Administered and Apparent Molar Activities
Vraka, C., Pichler, V., Berroterán-Infante, N., Wollenweber, T., Pillinger, A., Hohensinner, M., Fetty, L., Beitzke, D., Li, X., Philippe, C., Pallitsch, K., Mitterhauser, M., Hacker, M. & Wadsak, W., 14 Jan. 2019, in: Pharmaceuticals. 12, 1, 14 S., 12.Toward the Optimization of (+)-[11C]PHNO Synthesis: Time Reduction and Process Validation
Pfaff, S., Philippe, C., Nics, L., Berroteran-Infante, N., Pallitsch, K., Rami-Mark, C., Weidenauer, A., Sauerzopf, U., Willeit, M., Mitterhauser, M., Hacker, M., Wadsak, W. & Pichler, V., 2019, in: Contrast media & molecular imaging. 2019, 13 S., 4292596.PcxL and HpxL are flavin-dependent, oxime-forming N-oxidases in phosphonocystoximic acid biosynthesis in Streptomyces
Goettge, M. N., Cioni, J. P., Ju, K-S., Pallitsch, K. & Metcalf, W. W., 4 Mai 2018, in: Journal of Biological Chemistry. 293, 18, S. 6859-6868 10 S.Preclinical in Vitro and in Vivo Evaluation of [ 18F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer
Balber, T., Singer, J., Berroteran-Infante, N., Dumanic, M., Fetty, L., Fazekas-Singer, J., Vraka, C., Nics, L., Bergmann, M., Pallitsch, K., Spreitzer, H., Wadsak, W., Hacker, M., Jensen-Jarolim, E., Viernstein, H. & Mitterhauser, M., 2018, in: Contrast media & molecular imaging. 2018, 9 S., 1269830.Determination of the Absolute Configuration of (-)-Hydroxynitrilaphos and Related Biosynthetic Questions
Pallitsch, K., Happl, B. & Stieger, C., 7 Nov. 2017, in: Chemistry: A European Journal. 23, 62, S. 15655-15665 11 S.Phosphonodifluoropyruvate is a mechanism-based inhibitor of phosphonopyruvate decarboxylase from Bacteroides fragilis
Pallitsch, K., Rogers, M. P., Andrews, F. H., Hammerschmidt, F. & McLeish, M. J., 15 Aug. 2017, in: Bioorganic & Medicinal Chemistry. 25, 16, S. 4368-4374 7 S.In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [ 11C]SNAP-7941 and [ 18F]FE@SNAP reveal specific uptake in the ventricular system
Zeilinger, M., Dumanic, M., Pichler, F., Budinsky, L., Wadsak, W., Pallitsch, K., Spreitzer, H., Hacker, M., Mitterhauser, M. & Philippe, C., 14 Aug. 2017, in: Scientific Reports. 7, 10 S., 8054.Towards the biodegradation pathway of fosfomycin
Pallitsch, K., Schweifer, A., Roller, A. & Hammerschmidt, F., 19 Apr. 2017, in: Organic & Biomolecular Chemistry. 15, 15, S. 3276-3285 10 S.The Stereochemical Course of the α-Hydroxyphosphonate-Phosphate Rearrangement
Pallitsch, K., Roller, A. & Hammerschmidt, F., 6 Juli 2015, in: Chemistry: A European Journal. 21, 28, S. 10200-10206 7 S.Stereochemistry of alpha-Hydroxyphosphonate-Phosphate rearrangement
Pallitsch, K., Roller, A. & Hammerschmidt, F., 28 Juni 2014.Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates
van Staalduinen, L. M., McSorley, F. R., Schiessl, K., Seguin, J., Wyatt, P. B., Hammerschmidt, F., Zechel, D. L. & Jia, Z., 8 Apr. 2014, in: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 111, 14, S. 5171-5176 6 S.Determination of absolute configuration of the phosphonic acid moiety of fosfazinomycins
Schiessl, K., Roller, A. & Hammerschmidt, F., 14 Nov. 2013, in: Organic & Biomolecular Chemistry. 11, 42, S. 7420-7426 7 S.On the Electronic Structure of mer,trans-[RuCl3(1H-indazole)2(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study
Bucinsky, L., Büchel, G., Ponec, R., Rapta, P., Breza, M., Kozisek, J., Gall, M., Biskupic, S., Fronc, M., Schiessl, K., Cuzan, O., Prodius, D., Turta, C., Shova, S., Zajac, D. A. & Arion, V., 2013, in: European Journal of Inorganic Chemistry. 14, S. 2505-2519 15 S.Projekte
Die Synthese fluorierter seltener Zucker
Pallitsch, K.
2/01/20 → 1/01/23
Die ungewöhnlichen Enzyme des P
Pallitsch, K.
12/10/15 → 11/10/18
Metabolie pathways revealed - from marine microbes to modern diagnostics
Katharina Pallitsch (Invited speaker)
Aktivität: Vorträge › Vortrag › Science to Science
The synthesis of bifunctional phosphonic acids to study C-P lyase
Tamara Dinhof (Vortragende*r) & Katharina Pallitsch (Autor*in)
Aktivität: Vorträge › Vortrag › Science to Science
From 11C to 18F – Organic Chemistry as Potent Tool in Medicinal Chemistry
Katharina Pallitsch (Vortragende*r)
Aktivität: Vorträge › Vortrag › Science to Science
Studies on the Biodegradation of P-C Compounds - Synthesis of Phosphonic Acids with High ee
Katharina Pallitsch (Invited speaker)
Aktivität: Vorträge › Vortrag › Science to Science
Synthesis of 1-fluoro-1-deoxysedoheptulose - a possible new PET-tracer for tumour imaging
Katharina Pallitsch (Vortragende*r)
Aktivität: Vorträge › Vortrag › Science to Science
Studies on the Biodegradation of P-C Compounds – Synthesis of Phosphonic Acids with High ee
Katharina Pallitsch (Vortragende*r)
Aktivität: Vorträge › Vortrag › Science to Science
On the mode of action of two new PhnY and PhnZ homologs
Katharina Pallitsch (Vortragende*r)
Aktivität: Vorträge › Vortrag › Science to Science
A new general strategy for the synthesis of proteinogenic α-aminophosphonic acids of high enantiomeric excess
Katharina Pallitsch (Vortragende*r) & Thomas Kalina (Autor*in)
Aktivität: Vorträge › Vortrag › Science to Science
Structure elucidation of some unique biogenic phosphonates
Katharina Pallitsch (Vortragende*r)
Aktivität: Vorträge › Vortrag › Science to Science
Stereochemistry of alpha-Hydroxyphosphonate-Phosphate rearrangement
Katharina Pallitsch (Vortragende*r), Alexander Roller (Autor*in) & Friedrich Hammerschmidt (Autor*in)
Aktivität: Vorträge › Vortrag › Andere
Determination of the absolute configuration of the phosphonic acid part of fosfazinomycins.
Katharina Pallitsch (Vortragende*r) & Friedrich Hammerschmidt (Vortragende*r)
Aktivität: Vorträge › Vortrag › Andere
DETERMINATION OF THE ABSOLUTE CONFIGURATION OF THE PHOSPHONIC ACID PART OF FOSFAZINOMYCINS
Katharina Pallitsch (Vortragende*r)
Aktivität: Vorträge › Vortrag › Andere
Institut für Organische Chemie
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1090 Wien
Zimmer: 1109
T: +43-1-4277-52105