Department of Organic Chemistry
Postal address: Währingerstraße 38, 1090 Wien
Austria
Email: katharina.pallitsch@univie.ac.at
Phone: +43-1-4277-52105 or 52123
Research outputs
Decrypting the function of recurrent ancillary enzymes in bacterial phosphonate catabolism
Ruffolo, F., Zangelmi, E., Dinhof, T., Malatesta, M., Gerdol, M., Chin, J. P., Secchi, A., Rivetti, C., Pallitsch, K. & Peracchi, A., Jun 2024, In: FEBS Open Bio. 14, Supplement: 2, p. 153-154 P-11-003.Development and In Vivo Evaluation of Small-Molecule Ligands for Positron Emission Tomography of Immune Checkpoint Modulation Targeting Programmed Cell Death 1 Ligand 1
Bamminger, K., Pichler, V., Vraka, C., Limberger, T., Moneva, B., Pallitsch, K., Lieder, B., Zacher, A. S., Ponti, S., Benčurová, K., Yang, J., Högler, S., Kodajova, P., Kenner, L., Hacker, M. & Wadsak, W., 14 Mar 2024, In: Journal of Medicinal Chemistry. 67, 5, p. 4036-4062 27 p.Asymmetric Transfer Hydrogenation as a Key Step in the Synthesis of the Phosphonic Acid Analogs of Aminocarboxylic Acids
Dinhof, T., Kalina, T., Stanković, T., Braunsteiner, K., Rohrbach, P., Turhan, E., Gradwohl, A., Königshofer, A., Horak, J. & Pallitsch, K., 22 Dec 2023, In: Chemistry - A European Journal. 29, 72, e202302171.Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism
Zangelmi, E., Ruffolo, F., Dinhof, T., Gerdol, M., Malatesta, M., Chin, J. P., Rivetti, C., Secchi, A., Pallitsch, K. & Peracchi, A., 17 Nov 2023, In: Iscience. 26, 11, 108108.Synthesis of 4-Deoxy-4-Fluoro-D-Sedoheptulose: A Promising New Sugar to Apply the Principle of Metabolic Trapping
Scheibelberger, L., Stankovic, T., Pühringer, M., Kählig, H., Balber, T., Patronas, E. M., Rampler, E., Mitterhauser, M., Haschemi, A. & Pallitsch, K., 8 Nov 2023, In: Chemistry - A European Journal. 29, 62, e202302277.The Microbial Degradation of Natural and Anthropogenic Phosphonates
Ruffolo, F., Dinhof, T., Murray, L., Zangelmi, E., Chin, J. P., Pallitsch, K. & Peracchi, A., Oct 2023, In: Molecules. 28, 19, 6863.Fluorinated Analogues to the Pentuloses of the Pentose Phosphate Pathway
Scheibelberger, L., Stankovic, T., Liepert, K., Kienzle, A., Patronas, E. M., Balber, T., Mitterhauser, M., Haschemi, A. & Pallitsch, K., 14 Aug 2023, In: European Journal of Organic Chemistry. 26, 31, e202300339.On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach
Bamminger, K., Pichler, V., Vraka, C., Nehring, T., Pallitsch, K., Lieder, B., Hacker, M. & Wadsak, W., Jul 2023, In: Pharmaceuticals. 16, 7, 1051.The functional importance of bacterial oxidative phosphonate pathways
Pallitsch, K. & Zechel, D. L., Apr 2023, In: Biochemical Society Transactions. 51, 2, p. 487-499 13 p.Biosynthesis of the Fungal Organophosphonate Fosfonochlorin Involves an Iron(II) and 2-(Oxo)glutarate Dependent Oxacyclase
Gama, S. R., Stankovic, T., Hupp, K., Al Hejami, A., McClean, M., Evans, A., Beauchemin, D., Hammerschmidt, F., Pallitsch, K. & Zechel, D. L., 19 Jan 2022, In: ChemBioChem: a european journal of chemical biology. 23, 2, 8 p., e202100352.As Similar As Possible, As Different As Necessary - On-Site Laboratory Teaching during the COVID-19 Pandemic
Mosiagin, I., Pallitsch, K., Klose, S. I., Preinfalk, A. & Maulide, N., 12 Oct 2021, In: Journal of Chemical Education. 98, 10, p. 3143-3152 10 p.Towards understanding the magnetism of Os(iv) complexes: an ab initio insight
Ungur, L., Pallitsch, K., AlOthman, Z. A., Al-Kahtani, A. A. S., Arion, V. B. & Chibotaru, L. F., Aug 2021, In: Dalton Transactions. 50, 36, p. 12537-12546 10 p.Discovery of melanin-concentrating hormone receptor 1 in brown adipose tissue
Philippe, C., Klebermass, E-M., Balber, T., Kulterer, O. C., Zeilinger, M., Egger, G., Dumanic, M., Herz, C. T., Kiefer, F. W., Scheuba, C., Scherer, T., Fuernsinn, C., Vraka, C., Pallitsch, K., Spreitzer, H., Wadsak, W., Viernstein, H., Hacker, M. & Mitterhauser, M., Jun 2021, In: Annals of the New York Academy of Sciences. 1494, 1, p. 70-86 17 p.Overall Retention of Methyl Stereochemistry during B-12-Dependent Radical SAM Methyl Transfer in Fosfomycin Biosynthesis
McLaughlin, M., Pallitsch, K., Wallner, G., van der Donk, W. A. & Hammerschmidt, F., 25 May 2021, In: Biochemistry. 60, 20, p. 1587-1596 10 p.Discovery of a New, Recurrent Enzyme in Bacterial Phosphonate Degradation: (R)-1-Hydroxy-2-aminoethylphosphonate Ammonia-lyase
Zangelmi, E., Stankovic, T., Malatesta, M., Acquotti, D., Pallitsch, K. & Peracchi, A., 20 Apr 2021, In: Biochemistry. 60, 15, p. 1214-1225 12 p.C-H Bond Cleavage Is Rate-Limiting for Oxidative C-P Bond Cleavage by the Mixed Valence Diiron-Dependent Oxygenase PhnZ
Gama, S. R., Lo, B. S. Y., Seguin, J., Pallitsch, K., Hammerschmidt, F. & Zechel, D. L., 31 Dec 2019, In: Biochemistry. 58, 52, p. 5271-5280 10 p.(R)-[F-18]NEBIFQUINIDE: A promising new PET tracer for TSPO imaging
Berroteran-Infante, N., Kalina, T., Fetty, L., Janisch, V., Velasco, R., Vraka, C., Hacker, M., Haug, A. R., Pallitsch, K., Wadsak, W. & Mitterhauser, M., 15 Aug 2019, In: European Journal of Medicinal Chemistry. 176, p. 410-418 9 p.In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes
Balber, T., Bencurova, K., Kiefer, F. W., Kulterer, O. C., Klebermass, E-M., Egger, G., Tran, L., Wagner, K-H., Viernstein, H., Pallitsch, K., Spreitzer, H., Hacker, M., Wadsak, W., Mitterhauser, M. & Philippe, C., 11 Jun 2019, In: Frontiers in Endocrinology. 10, 324.Facilitated troubleshooting in (+)-[C-11]PHNO synthesis by investigation of reagents, byproducts, and intermediates
Pfaff, S., Philippe, C., Nics, L., Berroteran-Infante, N., Pallitsch, K., Rami-Mark, C., Weidenauer, A., Sauerzopf, U., Willeit, M., Mitterhauser, M., Hacker, M., Wadsak, W. & Pichler, V., May 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, p. 255-257 3 p.SNAPshots of the MCHR1: a Comparison Between the PET-Tracers [F-18]FE@SNAP and [C-11]SNAP-7941
Philippe, C., Zeilinger, M., Dumanic, M., Pichler, F., Fetty, L., Vraka, C., Balber, T., Wadsak, W., Pallitsch, K., Spreitzer, H., Lanzenberger, R., Hacker, M. & Mitterhauser, M., 15 Apr 2019, In: Molecular Imaging and Biology. 21, 2, p. 257-268 12 p.An Oxidative Pathway for Microbial Utilization of Methylphosphonic Acid as a Phosphate Source
Gama, S. R., Vogt, M., Kalina, T., Hupp, K., Hammerschmidt, F., Pallitsch, K. & Zechel, D. L., Apr 2019, In: ACS Chemical Biology. 14, 4, p. 735-741 7 p.Synthetic Phosphonic Acids as Potent Tools to Study Phosphonate Enzymology
Pallitsch, K., Kalina, T. & Stanković, T., Apr 2019, In: Synlett. 30, 7, p. 770-776 7 p.Synthesis and in vitro evaluation of new translocator protein ligands designed for positron emission tomography
Kalina, T., Berroterán-Infante, N., Schmitl, S., Vraka, C., Hacker, M., Mitterhauser, M., Pallitsch, K. & Wadsak, W., 1 Mar 2019, In: Future Medicinal Chemistry. 11, 6, p. 539-550 12 p.Optimization of the Automated Synthesis of [ 11C ]mHED—Administered and Apparent Molar Activities
Vraka, C., Pichler, V., Berroterán-Infante, N., Wollenweber, T., Pillinger, A., Hohensinner, M., Fetty, L., Beitzke, D., Li, X., Philippe, C., Pallitsch, K., Mitterhauser, M., Hacker, M. & Wadsak, W., 14 Jan 2019, In: Pharmaceuticals. 12, 1, 14 p., 12.Toward the Optimization of (+)-[11C]PHNO Synthesis: Time Reduction and Process Validation
Pfaff, S., Philippe, C., Nics, L., Berroteran-Infante, N., Pallitsch, K., Rami-Mark, C., Weidenauer, A., Sauerzopf, U., Willeit, M., Mitterhauser, M., Hacker, M., Wadsak, W. & Pichler, V., 2019, In: Contrast media & molecular imaging. 2019, 13 p., 4292596.PcxL and HpxL are flavin-dependent, oxime-forming N-oxidases in phosphonocystoximic acid biosynthesis in Streptomyces
Goettge, M. N., Cioni, J. P., Ju, K-S., Pallitsch, K. & Metcalf, W. W., 4 May 2018, In: Journal of Biological Chemistry. 293, 18, p. 6859-6868 10 p.Preclinical in Vitro and in Vivo Evaluation of [ 18F]FE@SUPPY for Cancer PET Imaging: Limitations of a Xenograft Model for Colorectal Cancer
Balber, T., Singer, J., Berroteran-Infante, N., Dumanic, M., Fetty, L., Fazekas-Singer, J., Vraka, C., Nics, L., Bergmann, M., Pallitsch, K., Spreitzer, H., Wadsak, W., Hacker, M., Jensen-Jarolim, E., Viernstein, H. & Mitterhauser, M., 2018, In: Contrast media & molecular imaging. 2018, 9 p., 1269830.Determination of the Absolute Configuration of (-)-Hydroxynitrilaphos and Related Biosynthetic Questions
Pallitsch, K., Happl, B. & Stieger, C., 7 Nov 2017, In: Chemistry: A European Journal. 23, 62, p. 15655-15665 11 p.Phosphonodifluoropyruvate is a mechanism-based inhibitor of phosphonopyruvate decarboxylase from Bacteroides fragilis
Pallitsch, K., Rogers, M. P., Andrews, F. H., Hammerschmidt, F. & McLeish, M. J., 15 Aug 2017, In: Bioorganic & Medicinal Chemistry. 25, 16, p. 4368-4374 7 p.In vivo evaluation of radiotracers targeting the melanin-concentrating hormone receptor 1: [ 11C]SNAP-7941 and [ 18F]FE@SNAP reveal specific uptake in the ventricular system
Zeilinger, M., Dumanic, M., Pichler, F., Budinsky, L., Wadsak, W., Pallitsch, K., Spreitzer, H., Hacker, M., Mitterhauser, M. & Philippe, C., 14 Aug 2017, In: Scientific Reports. 7, 10 p., 8054.Towards the biodegradation pathway of fosfomycin
Pallitsch, K., Schweifer, A., Roller, A. & Hammerschmidt, F., 19 Apr 2017, In: Organic & Biomolecular Chemistry. 15, 15, p. 3276-3285 10 p.The Stereochemical Course of the α-Hydroxyphosphonate-Phosphate Rearrangement
Pallitsch, K., Roller, A. & Hammerschmidt, F., 6 Jul 2015, In: Chemistry: A European Journal. 21, 28, p. 10200-10206 7 p.Stereochemistry of alpha-Hydroxyphosphonate-Phosphate rearrangement
Pallitsch, K., Roller, A. & Hammerschmidt, F., 28 Jun 2014.Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates
van Staalduinen, L. M., McSorley, F. R., Schiessl, K., Seguin, J., Wyatt, P. B., Hammerschmidt, F., Zechel, D. L. & Jia, Z., 8 Apr 2014, In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). 111, 14, p. 5171-5176 6 p.Determination of absolute configuration of the phosphonic acid moiety of fosfazinomycins
Schiessl, K., Roller, A. & Hammerschmidt, F., 14 Nov 2013, In: Organic & Biomolecular Chemistry. 11, 42, p. 7420-7426 7 p.On the Electronic Structure of mer,trans-[RuCl3(1H-indazole)2(NO)], a Hypothetical Metabolite of the Antitumor Drug Candidate KP1019: An Experimental and DFT Study
Bucinsky, L., Büchel, G., Ponec, R., Rapta, P., Breza, M., Kozisek, J., Gall, M., Biskupic, S., Fronc, M., Schiessl, K., Cuzan, O., Prodius, D., Turta, C., Shova, S., Zajac, D. A. & Arion, V., 2013, In: European Journal of Inorganic Chemistry. 14, p. 2505-2519 15 p.Projects
Die ungewöhnlichen Enzyme des P
Pallitsch, K.
12/10/15 → 11/10/18
The synthesis of fluorinated rare sugars
Pallitsch, K.
2/01/20 → 1/01/23
Metabolie pathways revealed - from marine microbes to modern diagnostics
Katharina Pallitsch (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
The synthesis of bifunctional phosphonic acids to study C-P lyase
Tamara Dinhof (Speaker) & Katharina Pallitsch (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
From 11C to 18F – Organic Chemistry as Potent Tool in Medicinal Chemistry
Katharina Pallitsch (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Studies on the Biodegradation of P-C Compounds - Synthesis of Phosphonic Acids with High ee
Katharina Pallitsch (Invited speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Synthesis of 1-fluoro-1-deoxysedoheptulose - a possible new PET-tracer for tumour imaging
Katharina Pallitsch (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Studies on the Biodegradation of P-C Compounds – Synthesis of Phosphonic Acids with High ee
Katharina Pallitsch (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
On the mode of action of two new PhnY and PhnZ homologs
Katharina Pallitsch (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
A new general strategy for the synthesis of proteinogenic α-aminophosphonic acids of high enantiomeric excess
Katharina Pallitsch (Speaker) & Thomas Kalina (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Structure elucidation of some unique biogenic phosphonates
Katharina Pallitsch (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Science to Science
Stereochemistry of alpha-Hydroxyphosphonate-Phosphate rearrangement
Katharina Pallitsch (Speaker), Alexander Roller (Contributor) & Friedrich Hammerschmidt (Contributor)
Activity: Talks and presentations › Talk or oral contribution › Other
Determination of the absolute configuration of the phosphonic acid part of fosfazinomycins.
Katharina Pallitsch (Speaker) & Friedrich Hammerschmidt (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
DETERMINATION OF THE ABSOLUTE CONFIGURATION OF THE PHOSPHONIC ACID PART OF FOSFAZINOMYCINS
Katharina Pallitsch (Speaker)
Activity: Talks and presentations › Talk or oral contribution › Other
Department of Organic Chemistry
Währinger Straße 38-42
1090 Wien
Room: 1109
T: +43-1-4277-52105