Dr. Katharina Pallitsch, Privatdoz. Bakk. MSc
Katharina Pallitsch
Ruffolo, F., Conciatori, S., Merici, G., Dinhof, T., Chin, J. P., Rivetti, C., Secchi, A., Pallitsch, K., & Peracchi, A. (2025). Genomic context analysis enables the discovery of an unusual NAD-dependent racemase in phosphonate catabolism. FEBS Journal. Advance online publication. https://doi.org/10.1111/febs.70130

Ruffolo, F., Zangelmi, E., Dinhof, T., Malatesta, M., Gerdol, M., Chin, J. P., Secchi, A., Rivetti, C., Pallitsch, K., & Peracchi, A. (2024). Decrypting the function of recurrent ancillary enzymes in bacterial phosphonate catabolism. FEBS Open Bio, 14(Supplement: 2), 153-154. Article P-11-003.

Bamminger, K., Pichler, V., Vraka, C., Limberger, T., Moneva, B., Pallitsch, K., Lieder, B., Zacher, A. S., Ponti, S., Benčurová, K., Yang, J., Högler, S., Kodajova, P., Kenner, L., Hacker, M., & Wadsak, W. (2024). Development and In Vivo Evaluation of Small-Molecule Ligands for Positron Emission Tomography of Immune Checkpoint Modulation Targeting Programmed Cell Death 1 Ligand 1. Journal of Medicinal Chemistry, 67(5), 4036-4062. https://doi.org/10.1021/acs.jmedchem.3c02342

Dinhof, T., Kalina, T., Stanković, T., Braunsteiner, K., Rohrbach, P., Turhan, E., Gradwohl, A., Königshofer, A., Horak, J., & Pallitsch, K. (2023). Asymmetric Transfer Hydrogenation as a Key Step in the Synthesis of the Phosphonic Acid Analogs of Aminocarboxylic Acids. Chemistry - A European Journal, 29(72), Article e202302171. https://doi.org/10.1002/chem.202302171

Zangelmi, E., Ruffolo, F., Dinhof, T., Gerdol, M., Malatesta, M., Chin, J. P., Rivetti, C., Secchi, A., Pallitsch, K., & Peracchi, A. (2023). Deciphering the role of recurrent FAD-dependent enzymes in bacterial phosphonate catabolism. Iscience, 26(11), Article 108108. https://doi.org/10.1016/j.isci.2023.108108

Scheibelberger, L., Stankovic, T., Pühringer, M., Kählig, H., Balber, T., Patronas, E. M., Rampler, E., Mitterhauser, M., Haschemi, A., & Pallitsch, K. (2023). Synthesis of 4-Deoxy-4-Fluoro-D-Sedoheptulose: A Promising New Sugar to Apply the Principle of Metabolic Trapping. Chemistry - A European Journal, 29(62), Article e202302277. https://doi.org/10.1002/chem.202302277

Ruffolo, F., Dinhof, T., Murray, L., Zangelmi, E., Chin, J. P., Pallitsch, K., & Peracchi, A. (2023). The Microbial Degradation of Natural and Anthropogenic Phosphonates. Molecules, 28(19), Article 6863. https://doi.org/10.3390/molecules28196863

Scheibelberger, L., Stankovic, T., Liepert, K., Kienzle, A., Patronas, E. M., Balber, T., Mitterhauser, M., Haschemi, A., & Pallitsch, K. (2023). Fluorinated Analogues to the Pentuloses of the Pentose Phosphate Pathway. European Journal of Organic Chemistry, 26(31), Article e202300339. https://doi.org/10.1002/ejoc.202300339


Pallitsch, K., & Zechel, D. L. (2023). The functional importance of bacterial oxidative phosphonate pathways. Biochemical Society Transactions, 51(2), 487-499. https://doi.org/10.1042/BST20220479

Gama, S. R., Stankovic, T., Hupp, K., Al Hejami, A., McClean, M., Evans, A., Beauchemin, D., Hammerschmidt, F., Pallitsch, K., & Zechel, D. L. (2022). Biosynthesis of the Fungal Organophosphonate Fosfonochlorin Involves an Iron(II) and 2-(Oxo)glutarate Dependent Oxacyclase. ChemBioChem: a european journal of chemical biology, 23(2), Article e202100352. https://doi.org/10.1002/cbic.202100352


Ungur, L., Pallitsch, K., AlOthman, Z. A., Al-Kahtani, A. A. S., Arion, V. B., & Chibotaru, L. F. (2021). Towards understanding the magnetism of Os(iv) complexes: an ab initio insight. Dalton Transactions, 50(36), 12537-12546. https://doi.org/10.1039/d1dt01558c

Philippe, C., Klebermass, E.-M., Balber, T., Kulterer, O. C., Zeilinger, M., Egger, G., Dumanic, M., Herz, C. T., Kiefer, F. W., Scheuba, C., Scherer, T., Fuernsinn, C., Vraka, C., Pallitsch, K., Spreitzer, H., Wadsak, W., Viernstein, H., Hacker, M., & Mitterhauser, M. (2021). Discovery of melanin-concentrating hormone receptor 1 in brown adipose tissue. Annals of the New York Academy of Sciences, 1494(1), 70-86. https://doi.org/10.1111/nyas.14563




Berroteran-Infante, N., Kalina, T., Fetty, L., Janisch, V., Velasco, R., Vraka, C., Hacker, M., Haug, A. R., Pallitsch, K., Wadsak, W., & Mitterhauser, M. (2019). (R)-[F-18]NEBIFQUINIDE: A promising new PET tracer for TSPO imaging. European Journal of Medicinal Chemistry, 176, 410-418. https://doi.org/10.1016/j.ejmech.2019.05.008

Balber, T., Bencurova, K., Kiefer, F. W., Kulterer, O. C., Klebermass, E.-M., Egger, G., Tran, L., Wagner, K.-H., Viernstein, H., Pallitsch, K., Spreitzer, H., Hacker, M., Wadsak, W., Mitterhauser, M., & Philippe, C. (2019). In vitro Radiopharmaceutical Evidence for MCHR1 Binding Sites in Murine Brown Adipocytes. Frontiers in Endocrinology, 10, Article 324. https://doi.org/10.3389/fendo.2019.00324

Pfaff, S., Philippe, C., Nics, L., Berroteran-Infante, N., Pallitsch, K., Rami-Mark, C., Weidenauer, A., Sauerzopf, U., Willeit, M., Mitterhauser, M., Hacker, M., Wadsak, W., & Pichler, V. (2019). Facilitated troubleshooting in (+)-[C-11]PHNO synthesis by investigation of reagents, byproducts, and intermediates. Journal of Labelled Compounds and Radiopharmaceuticals, 62, 255-257.

Profile photoKatharina Pallitsch

Department of Organic Chemistry
Postal address: Währingerstraße 38, 1090 Wien
Austria
Email: katharina.pallitsch@univie.ac.at
Phone: +43-1-4277-52105 or 52123

Research outputs

The functional importance of bacterial oxidative phosphonate pathways

Pallitsch, K. & Zechel, D. L. (Corresponding author), Apr 2023, In: Biochemical Society Transactions. 51, 2, p. 487-499 13 p.

Synthetic Phosphonic Acids as Potent Tools to Study Phosphonate Enzymology

Pallitsch, K. (Corresponding author), Kalina, T. & Stanković, T., Apr 2019, In: Synlett. 30, 7, p. 770-776 7 p.

Determination of the Absolute Configuration of (-)-Hydroxynitrilaphos and Related Biosynthetic Questions

Pallitsch, K. (Corresponding author), Happl, B. & Stieger, C., 7 Nov 2017, In: Chemistry: A European Journal. 23, 62, p. 15655-15665 11 p.

Phosphonodifluoropyruvate is a mechanism-based inhibitor of phosphonopyruvate decarboxylase from Bacteroides fragilis

Pallitsch, K., Rogers, M. P., Andrews, F. H., Hammerschmidt, F. & McLeish, M. J., 15 Aug 2017, In: Bioorganic & Medicinal Chemistry. 25, 16, p. 4368-4374 7 p.

Towards the biodegradation pathway of fosfomycin

Pallitsch, K. (Corresponding author), Schweifer, A., Roller, A. & Hammerschmidt, F., 19 Apr 2017, In: Organic & Biomolecular Chemistry. 15, 15, p. 3276-3285 10 p.

The Stereochemical Course of the α-Hydroxyphosphonate-Phosphate Rearrangement

Pallitsch, K., Roller, A. & Hammerschmidt, F. (Corresponding author), 6 Jul 2015, In: Chemistry: A European Journal. 21, 28, p. 10200-10206 7 p.

Stereochemistry of alpha-Hydroxyphosphonate-Phosphate rearrangement

Pallitsch, K., Roller, A. & Hammerschmidt, F., 28 Jun 2014.

Determination of absolute configuration of the phosphonic acid moiety of fosfazinomycins

Schiessl, K., Roller, A. & Hammerschmidt, F. (Corresponding author), 14 Nov 2013, In: Organic & Biomolecular Chemistry. 11, 42, p. 7420-7426 7 p.

Projects

Die ungewöhnlichen Enzyme des P

Pallitsch, K. (Project Lead)

12/10/1511/10/18

Phosphonate-based enzyme inhibitors

Pallitsch, K. (Project Lead)

28/04/2527/10/28

The synthesis of fluorinated rare sugars

Pallitsch, K. (Project Lead)

2/01/201/01/23

Metabolie pathways revealed - from marine microbes to modern diagnostics

Pallitsch, K. (Invited speaker)

30 Aug 2023

Activity: Talks and presentationsTalk or oral contributionScience to Science


The synthesis of bifunctional phosphonic acids to study C-P lyase

Dinhof, T. (Speaker) & Pallitsch, K. (Contributor)

12 May 2022

Activity: Talks and presentationsTalk or oral contributionScience to Science


From 11C to 18F – Organic Chemistry as Potent Tool in Medicinal Chemistry

Pallitsch, K. (Speaker)

5 Jun 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Studies on the Biodegradation of P-C Compounds - Synthesis of Phosphonic Acids with High ee

Pallitsch, K. (Invited speaker)

24 Apr 2019

Activity: Talks and presentationsTalk or oral contributionScience to Science


Synthesis of 1-fluoro-1-deoxysedoheptulose - a possible new PET-tracer for tumour imaging

Pallitsch, K. (Speaker)

26 Aug 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


Studies on the Biodegradation of P-C Compounds – Synthesis of Phosphonic Acids with High ee

Pallitsch, K. (Speaker)

23 Aug 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


On the mode of action of two new PhnY and PhnZ homologs

Pallitsch, K. (Speaker)

8 Jul 2018

Activity: Talks and presentationsTalk or oral contributionScience to Science


A new general strategy for the synthesis of proteinogenic α-aminophosphonic acids of high enantiomeric excess

Pallitsch, K. (Speaker) & Kalina, T. (Contributor)

25 Sept 201728 Sept 2017

Activity: Talks and presentationsTalk or oral contributionScience to Science


Structure elucidation of some unique biogenic phosphonates

Pallitsch, K. (Speaker)

4 Jun 20169 Jun 2016

Activity: Talks and presentationsTalk or oral contributionScience to Science


Stereochemistry of alpha-Hydroxyphosphonate-Phosphate rearrangement

Pallitsch, K. (Speaker), Roller, A. (Contributor) & Hammerschmidt, F. (Contributor)

28 Jun 20142 Jul 2014

Activity: Talks and presentationsTalk or oral contributionOther


Determination of the absolute configuration of the phosphonic acid part of fosfazinomycins.

Pallitsch, K. (Speaker) & Hammerschmidt, F. (Speaker)

23 Sept 201326 Sept 2013

Activity: Talks and presentationsTalk or oral contributionOther


DETERMINATION OF THE ABSOLUTE CONFIGURATION OF THE PHOSPHONIC ACID PART OF FOSFAZINOMYCINS

Pallitsch, K. (Speaker)

23 Sept 2013

Activity: Talks and presentationsTalk or oral contributionOther


Department of Organic Chemistry

Währinger Straße 38-42
1090 Wien
Room: 1109

T: +43-1-4277-52105

katharina.pallitsch@univie.ac.at